葉素玲臺灣大學:心理學研究所陳馨梅Chen, Hsin-MeiHsin-MeiChen2010-05-042018-06-282010-05-042018-06-282008U0001-0907200818083000http://ntur.lib.ntu.edu.tw//handle/246246/178654杏仁核對於情緒刺激的反應是否受到注意力之調控，已被廣泛討論多時，但大多數的證據來自於情緒臉孔之研究，注意力對於情緒詞所產生的影響則鮮為人知。在此研究中，以中文雙字詞作為刺激材料，我們藉由事件關聯功能性磁振造影，探討參與情緒詞處理之相關腦區是否受到注意力之影響，因而呈現不同之反應。在腦部造影的過程中，參與者依照指示將注意力置於中央凝視點之上下或左右兩個位置，在接續的每個嘗試中，上下及左右四個位置將隨機呈現一對中文詞和一對房子圖片，參與者被要求在刺激畫面出現時，判斷出現於“注意位置”之一對刺激是否相同，無論其為文字或者房子。在掃描過程中，參與者的反應時間、正確率及眼動表現也同時予以紀錄。實驗結果顯示，當比較注意力放置於中文詞相對於不注意(注意力放置於房子圖片)時，中性詞所呈現的大腦活化反應和之前其他作者以中文詞作為視覺刺激得到之活化反應相一致；正向情緒詞沒有呈現任何有差異之大腦活化，而負向情緒詞僅有在左側下額葉呈現較高的活化反應。相反地，當比較不注意中文詞相對於注意中文詞時，負向情緒詞呈現了廣泛的大腦活化反應，包括杏仁核。此研究結果顯示，當注意力擺放至負向情緒詞時，可能引發一個壓制性的機制運作，以抑制杏仁核的反應。Whether attention can modulate amygdala response to emotional materials has been hotly debated, and most evidence comes from emotional facial expressions which have much ecological significance. In contrast, little is known about the influence of attention on processing of emotional words as revealed by brain activation. We adopted an event-related fMRI paradigm to investigate whether brain responses to emotional words are affected by spatial attention using Chinese two-character words as stimuli. During the scan, the participant’s attention was directed to the horizontal or vertical locations which contain pairs of Chinese words or line-drawing houses, and he/she was required to indicate whether the pair of stimuli at the pre-specified locations were the same or different while ignoring the other irrelevant pair of stimuli. Reaction time, accuracy, and eye movements were recorded, and functional imaging data were acquired. Results showed that while neutral words at attended locations versus unattended locations produced brain activation patterns consistent with the reports of previous studies with Chinese words as visual stimuli, pleasant words showed no differential activation and unpleasant words evoked higher activation only in inferior frontal gyrus. Conversely, unpleasant words at unattended locations versus attended locations elicited activities in brain regions including amygdala, indicating possible attentional suppression to amygdala’s response to unpleasant words.1. INTRODUCTION………………..1.1. Brain areas involved with emotional processing………………..1.2. Effect of attention on emotional processing in amygdale....................2.3. Processing of emotional words....................4.4. Aim of the present study………………..6. MATERIALS AND METHODS………………..8.1 Participants………………..8.2 Stimuli………………..8.3 Experimental task………………..10.4. Data acquisition………………..12.5. Data analysis………………..12. RESULTS………………..16.1 Behavioral performance………………..16.2 fMRI data………………..17. DISCUSSION………………..21. CONCLUSIONS………………..24EFERENCES………………..25ABLES………………..29IGURES………………..37application/pdf1920233 bytesapplication/pdfen-US注意力情緒中文詞功能性磁振造影attentionemotionChinese wordsfMRIhttp://ntur.lib.ntu.edu.tw/bitstream/246246/178654/1/ntu-97-R95227104-1.pdf