MONG-WEI LINYIH-LEONG CHANGLee Y.-C.PEI-MING HUANG2021-10-082021-10-0820091569-9293https://www.scopus.com/inward/record.uri?eid=2-s2.0-69249089826&doi=10.1510%2ficvts.2009.206169&partnerID=40&md5=61745e501976b3994cf4f1f4321214cdhttps://scholars.lib.ntu.edu.tw/handle/123456789/584370Mediastinal paraganglioma is a rare and slow growing neurogenic tumor. Here, we describe a 49-year-old woman with a non-functional posterior mediastinal paraganglioma. Video-assisted thoracoscopic surgery for tumor excision failed due to massive bleeding. The tumor[as excised successfully by lateral thoracotomy with bipolar electrocautery 1 week after the first operation. Mediastinal paraganglioma remains a surgical challenge due to its hypervascular character and firm adhesion to adjacent mediastinal structure. Since the nonfunctional posterior mediastinal paraganglioma is often diagnosed after operation, it should be regarded as a differential diagnosis of mediastinal mass, especially if surgeons experience unexpected massive bleeding during operation.[SDGs]SDG3adult; article; bleeding; cancer surgery; case report; cauterization; computer assisted tomography; female; human; mediastinum tumor; paraganglioma; priority journal; thoracotomy; treatment failure; Blood Loss, Surgical; Diagnosis, Differential; Electrocoagulation; Female; Hemostasis, Surgical; Humans; Magnetic Resonance Imaging; Mediastinal Neoplasms; Middle Aged; Paraganglioma, Extra-Adrenal; Reoperation; Thoracic Surgery, Video-Assisted; Thoracotomy; Tomography, X-Ray Computed; Treatment Failurejournal article10.1510/icvts.2009.206169194911232-s2.0-69249089826