Lin M.-J.PEI-JER CHENLuoh M.-C.2021-07-032021-07-0320121042-0533https://www.scopus.com/inward/record.uri?eid=2-s2.0-84984571806&doi=10.1002%2fajhb.22267&partnerID=40&md5=71a5abaf33d288624ae1990493e01b42https://scholars.lib.ntu.edu.tw/handle/123456789/568500Objective: Mothers sero-positive for hepatitis B are slightly more likely to have a son. It is not known whether it is ever having HBV (HBsAg[+]) or currently active HBV (HBeAg[+]) which is associated with having a son. Method: Multivariable linear regression was used to assess the adjusted association of HBeAg(+) with offspring sex in all (90%) births (?3 million) in Taiwan from 1988 to 1999. Results: Totally, 5% of mothers were HBeAg(+). HBeAg(+) mothers were slightly more likely to have a son (sex ratio 108 rather than 106) adjusted for HBsAg, birth order, mother's age, birth year, and area of residence. Conclusion: At a population level HBV status makes little difference to the sex ratio at birth. ? 2012 Wiley Periodicals, Inc.[SDGs]SDG3Hepatitis B virusjournal article10.1002/ajhb.222672-s2.0-84984571806