2014-08-012024-05-13https://scholars.lib.ntu.edu.tw/handle/123456789/645948摘要：於維持姿勢穩定下進行另一項活動稱為姿勢-上姿勢作業，其牽涉到複雜的注意力課題。動作注意力可分為內聚焦(internal focus)與外聚焦(external focus)，過去研究多支持使用外聚焦策略會有較佳的動作表現。然而，姿勢難度可能是影響聚焦策略合適性的關鍵因素，於單一難度下適用之策略無法套用在所有情況，且目前研究多以行為量測為主，缺乏神經生理證據支持。本三年期計畫擬利用 H反射與腦電圖量測，配合行為表現分析，整合動作、神經與認知科學，探討老年人與巴金森氏症患者，於不同姿勢難度下，以內、外聚焦策略執行上姿勢作業，對姿勢-上姿勢活動控制的影響。第一年計畫著重「老化與運動神經元活動」：藉由 H反射，探討老年人於坐、站姿下，上姿勢動作注意力對姿勢-上姿勢活動外在行為表現與運動神經元興奮度的影響；第二年計畫著重「巴金森氏症與運動神經元活動」：探討巴金森氏症患者於不同坐姿難度下，上姿勢動作注意力對活動表現與運動神經元興奮度的影響；第三年計畫著重「巴金森氏症與大腦活動」：藉由腦電圖事件相關電位與動作相關電位，探討巴金森氏症患者於不同坐姿難度下，上姿勢動作注意力對活動表現與大腦資源運用的影響。本計畫完成將可釐清老年人與巴金森氏症患者，其上姿勢動作注意力對姿勢-上姿勢活動控制之神經生理機制，並可做為臨床訓練平衡與多重作業時，注意力引導之參考。 <br> Abstract: Inherent with intricate allocation of brain resource and attention shift, postural-suprapostural task is defined as postural control takes place while the other concurrent task is being performed. Recent studies have indicated that attentional focusing alters attention allocation in the brain as well as motor performance of a postural-suprapostural task. Also, most studies have demonstrated benefits of inducing an external focus relative to internal focus for motor performance. However, postural difficulty might be a critical factor for choosing an appropriate focusing strategy, and the strategy used in a particular difficulty level do not always generalize to other difficulty levels. Besides, despite a lot of studies have been done, current findings are confined to behavioral observations for lacking direct neural evidence. With the uses of H-reflex, EEG and behavioral measures, the purpose of the 3-year research project is to investigate the differences in performance quality and intrinsic neural mechanisms of a postural-suprapostural task for older adults and patients with Parkinson’s disease, by adopting external and internal focus strategies for suprapostural task under different posture difficulties. In the first year, we will characterize suprapostural focusing effect on reciprocity of a postural-suprapostural task, with a special focus on modulation of motoneuron excitability in sitting and standing posture for healthy young and older adults using H-reflex technique. In the second year, the adaptive selection of suprapostural focusing strategy and the modulation of motoneuron excitability will be investigated for patients with Parkinson’s disease by varying the sitting surface (stable/unstable surface). In the third year, we will investigate suprapostural focusing effect on brain resource allocation for patients with Parkinson’s disease, in light of event-related potential and movement-related potential. The present project is expected to have significant contributions not only to gain a better insight to neural correlates of concurrent postural and motor suprapostural tasks with internal/external suprapostural focusing strategy under different posture difficulties, but to optimize treatment strategy for older adults and patients with Parkinson’s disease with balance or multi-tasking disturbances.注意力H反射腦電圖老化巴金森氏症姿勢平衡AttentionH-reflexEEGAgingParkinsonPosture balance