Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer

Hashimoto, AyumiAyumiHashimotoSarker, DebashisDebashisSarkerReebye, VikashVikashReebyeJarvis, ShebaShebaJarvisSodergren, Mikael HMikael HSodergrenKossenkov, AndrewAndrewKossenkovSanseviero, EmilioEmilioSansevieroRaulf, NinaNinaRaulfVasara, JenniJenniVasaraAndrikakou, PinelopiPinelopiAndrikakouMeyer, TimTimMeyerKAI-WEN HUANG...etc.2021-11-262021-11-262021-11-0110780432https://scholars.lib.ntu.edu.tw/handle/123456789/588066To evaluate the mechanisms of how therapeutic upregulation of the transcription factor, CCAAT/enhancer-binding protein alpha (C/EBPα), prevents tumor progression in patients with advanced hepatocellular carcinoma (HCC) and in different mouse tumor models.en[SDGs]SDG3Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancerjournal article10.1158/1078-0432.CCR-21-0986344079722-s2.0-85118374093https://api.elsevier.com/content/abstract/scopus_id/85118374093