Shang-Yu ChenWeng T.-H.WEN-PIN TSENGCHIA-MING FULin H.-W.Liao C.-H.Lee T.-F.PO-REN HSUEHCHENG-CHUNG FANGSHEY-YING CHEN2021-05-072021-05-0720180732-8893https://scholars.lib.ntu.edu.tw/handle/123456789/560608Few studies analyzed the association between blood culture time to positivity (TTP) and risk of complicated nontyphoidal Salmonella (NTS) bacteremia. We conducted a retrospective study of 206 patients (aged 60.4 ± 17.4 years) with NTS bacteremia during a 30-month period. Complicated NTS bacteremia was defined as the presence of 30-day mortality, complicated infection requiring surgery or abscess drainage, or requirement of intensive care unit admission. Serogroup D (75.7%) was the predominant isolates. Malignancy (44.7%) was the most prevalent comorbidity. Patients with rapid TTP (<10 h) were more likely to have thrombocytopenia, septic shock, persistent bacteremia, complicated infection, and a higher intensive care unit admission rate. In multivariate logistic regression model, a TTP <10 h was an independent predictor for complicated NTS bacteremia (adjusted odd ratio, 5.683, 95% confidence interval, 2.396–13.482). Our study showed that blood culture TTP provides important diagnostic and prognostic information in the treatment of NTS bacteremia patients. ? 2018[SDGs]SDG3abscess drainage; adult; Article; bacteremia; blood culture; blood group typing; clinical outcome; cohort analysis; comorbidity; controlled study; disease association; female; hospital admission; human; independent variable; infection complication; intensive care unit; major clinical study; male; middle aged; mortality; nonhuman; predictor variable; priority journal; retrospective study; Salmonella; septic shock; thrombocytopenia; aged; bacteremia; blood culture; evaluation study; isolation and purification; procedures; prognosis; Salmonella; salmonellosis; time factor; very elderly; young adult; Adult; Aged; Aged, 80 and over; Bacteremia; Blood Culture; Female; Humans; Male; Middle Aged; Prognosis; Retrospective Studies; Salmonella; Salmonella Infections; Time Factors; Young Adultjournal article10.1016/j.diagmicrobio.2018.02.005295264502-s2.0-85043330481