2018-08-012024-05-18https://scholars.lib.ntu.edu.tw/handle/123456789/699989摘要：超導量子干涉元件(superconducting quantum interference device, SQUID)是目前世界上已實用化的最敏感磁性感測元件， 其可量測到地球磁場十億分之一以下的磁場強度(~1 femto-Tesla)，所以在極微小磁場量測方面的應用非常重要。在這子計畫工作中， SQUID陣列與高解析度腦磁圖(MEG)的結合並應用於動物腦生理功能和病理診斷的研究，是件創新的研究構想。目前為止還沒有類似的研究報告。這個子計畫嘗試製作出高靈敏度高溫超導量子干涉元件，並研究其物理性質。目標將溫度在77 K時訊降至10 micro Phi0/Hz^1/2(@100 Hz)以下。此外，SQUID元件將與電路中的低阻放大器串聯，以克服SQUID陣列上的串音效應。此研究結果可作為高空間與時間解析度的動物腦磁圖像掃描系統（子計劃3）和圖像處理技術（子計劃4）發展的基礎。<br> Abstract: Nowadays, superconducting Quantum Interference Device (SQUID) is the most sensitive magnetic detector in the world. It can measure the intensity of magnetic field of~ 10-15 Tesla, which is below one billionth of the Earth`s magnetic, and thus plays an important role for the application on detecting extremely small magnetic field. Especially, it has been applied to the detection of tiny biological magnetic fields. In this work, the SQUID arrays combined with high-resolution magnetoencephalography (MEG) will be developed for the study on animal brain physiological functions and pathological diagnosis, being an advance tool for innovative researches. There is still no similar research ideas reported. This sub-project attempts to fabricate high-sensitive high-Tc SQUIDs and arrays, and investigate the device physical properties. The goal is to get the magnetic flux noise that is decreased to be below 10 micro Phi0/Hz^1/2(@ 77 K, 100 Hz). Furthermore, the SQUIDs will be in-serial connected with low-impedance amplifiers in the electric circuits to overcome the crosstalk effect on the SQUID arrays. The results can be as the basis for the developments of animal brain magnetic image scanning system (sub-project 3) and image processing technology (sub-project 4) with high time and spatial resolutions高溫超導量子干涉元件磁性感測元件陣列串音效應HTS SQUIDmagnetic detectorarraycrosstalk