2016-01-012024-05-17https://scholars.lib.ntu.edu.tw/handle/123456789/694449摘要：黴菌毒素為黴菌產生之次級代謝物，對人體及畜禽均會產生嚴重的危害。穀物在採收前後均有可能受黴菌毒素污染，故其防範極為不易。而目前全球氣候暖化的結果，穀物受黴菌毒素污染的情形更為普遍。此外，大部份的黴菌毒素性質安定，加工後依然會殘留在食品或飼料中。畜禽食用受黴菌毒素污染的飼料將影響其生長繁殖性能，導致經濟上嚴重的損失。目前去除黴菌毒素的方法包括物理法、化學法與生物法，其中又因為生物法具有高效率、專一且對營養成分破壞較小等優點，故最具發展性。本計畫擬延續之前的研究成果，將2株對黴菌毒素具有分解能力的菌株Bacillus licheniformis CK1和Bacillus amyloliquefaciens LN，以及1株益生菌株Bacillus subtilis AC，製備成混合菌株之微生物製劑，並將該微生物製劑分別添加於一般肉雞飼料中或含黴菌毒素的肉雞飼料中，以評估其做為肉雞飼料用益生菌及黴菌毒素解毒劑之可行性。 <br> Abstract: Mycotoxins, the toxin secondary metabolites produced by fungi, are heat-stable and cannot be destroyed in most food and feed processes. The contaminations of mycotoxin in grains can happen pre- and post-harvest stage, thus it’s extremely difficult to control the spread of mycotoxins. Moreover, the change of global climate, such as “green-house effect”, has created an environment more favorable for the growth of some fungi. As a consequence, the economical loss associated with impaired animal health and performance due to consumption of mycotoxins has become a serious issue in the industry. Traditionally, elimination of contaminated mycotoxins in feed can be achieved by physical, chemical or biological methods. Among these detoxifying methods, the biological approach is more specific and efficient than the other methods. This research aims at evaluating the formulation of 3 bacterial strains, Bacillus licheniformis CK1, Bacillus amyloliquefaciens LN, and Bacillus subtilis AC, as a mycotoxin-degrading and probiotic agent in poultry production. This bacterial agent will be added into broiler feed or mycotoxin-contaminated feed to evaluate its mycotoxin-detoxifying and probiotic activities.地衣芽孢桿菌液化澱粉芽孢桿菌微生物製劑黴菌毒素Bacillus licheniformisBacillus amyloliquefaciensmicrobial agentmycotoxin