國立臺灣大學醫學院復健科謝正宜2006-07-262018-07-132006-07-262018-07-131999-07-31http://ntur.lib.ntu.edu.tw//handle/246246/28953血管阻抗描述血壓與血流脈波頻譜的 動態比值關係，是該位置下游血管負載的 重要指標。本研究利用臨床超音波系統開 發非侵入式動脈管徑脈動量測技術，結合 都卜勒血流計以推算血管阻抗，協助血管 相關疾病診斷。大動脈血管近乎彈性，我 們可由管壁之脈動推算血壓脈波。週邊 血管的血壓可以用觸診壓力計取得。在 同一斷面取得血管中心的流速就可以推 算血管阻抗。以頸動脈阻抗量測結果為 例，單側阻塞性腦中風病人正常邊與正常 人分析結果大致相同，阻塞邊之特徵阻抗 皆大於沒有阻塞邊，且在第四諧頻之前有 阻抗增加的趨勢。而單側出血性之腦中風 病人兩邊低頻阻抗皆有上升之趨勢。Vascular impedance that describes the spectral relationship of blood pressure and flow is an important index for vascular load downstream. In this study, clinical ultrasound was used to develop a non-invasive technique for measuring diameter pulsation. By coupling with Doppler velocimetry, the vascular impedance can be calculated. Since the central artery is nearly elastic, the blood pressure is directly related to the change of diameter. For the peripheral arteries, the palpating pressure is recorded to account for the vascular visco-elasticity. In the study of vascular impedance at the common carotid artery (CCA), we found the abnormal side of stroke patients with oneside occlusion had a higher mean resistance than the normal side and their vascular impedance at frequencies above the fourth harmonic increased. For patients with oneside hemorrhagic infarction, both-sides of their CCA impedance increased at lower frequencies indicating higher afterload.application/pdf290389 bytesapplication/pdfzh-TW國立臺灣大學醫學院復健科腦中風超音波血管阻抗StrokeUltrasoundVascularimpedanceotherhttp://ntur.lib.ntu.edu.tw/bitstream/246246/28953/1/882314B002285.pdf