LIN-CHI CHENWeng, Jui-HongJui-HongWengLee, Pei-WeiPei-WeiLee2025-05-132025-05-132018-10https://www.scopus.com/record/display.uri?eid=2-s2.0-105000088448&origin=resultslisthttps://scholars.lib.ntu.edu.tw/handle/123456789/729257This chapter describes and discusses the cutting-edge developments of “analytical aptamers” and “aptasensing”. These two are the two main pillars of aptamer diagnostics. The chapter aims to help readers quickly understand how innovations of aptamer diagnostics have been planned and realized. It also explores the novel aptasensing platforms - from assays and sensors to instrumental analyses. The chapter describes the frontiers of analytical aptamer selection and probe design. The approaches of aptamer probe design can be described from the following two aspects - working with as-selected aptamers versus specialized aptamer selection. The chapter further provides a brief of the emerging applications of aptamer diagnostics in the fields of human disease diagnosis, food/environmental monitoring, therapeutic drug assessment, and new molecular biology applications. These applications help to depict the picture of the continued growing, prosperous future for analytical aptamers.falseanalytical aptamer selectionaptamer diagnosticsaptamer probe designaptasensing platformsinstrumental analyses[SDGs]SDG11book part10.1002/9783527806799.ch132-s2.0-105000088448