Hsu C.-PLiu Y.-HBoobalan RLin Y.-FChein R.-JCHING-WEN CHIU2021-08-032021-08-0320212767333https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106438385&doi=10.1021%2facs.organomet.1c00036&partnerID=40&md5=6123a2eb808dd414909e5e441544d6cdhttps://scholars.lib.ntu.edu.tw/handle/123456789/575713Although the application of cationic aluminum complexes in catalysis has been extensively investigated, the incorporation of an aluminum cation into a chiral environment is less explored. In this study, a C2-symmetric chiral tetra-coordinate aluminum cation [3]+ bearing two chiral amino alcohol-derived ligands was prepared from commercially available starting materials in two steps. The high Lewis acidity of [3]+ exceeding that of B(C6F5)3 was verified by a competition binding experiment. Preliminary catalytic activity studies of [3]+ revealed that the tetra-coordinate aluminum cation is effective in accomplishing high conversion in all cases. However, the presence of a labile N?Al bond diminishes the enantioselectivity of the activation process. ? 2021 American Chemical SocietyCatalysis; Catalyst activity; Positive ions; Activation process; Aluminum cation; Aluminum complexes; Chiral amino alcohols; Chiral environment; High conversions; Lewis acidity; Tetra coordinate; Aluminum compoundsjournal article10.1021/acs.organomet.1c000362-s2.0-85106438385