Unique clinical characteristics and SCN5A mutations in patients with Brugada syndrome in Taiwan

JYH-MING JIMMY JUANGCHIA-TI TSAILIAN-YU LINYEN BIN LIUCHIH-CHIEH YUHWANG, JUEY-JENJUEY-JENHWANGJIEN-JIUN CHENChiu, Fu-ChunFu-ChunChiuWEN-JONE CHENTseng, Chuen-DenChuen-DenTsengFU-TIEN CHIANGHUEI-MING YEHSherri Yeh, Shih-FanShih-FanSherri YehLING-PING LAIJIUNN-LEE LIN2022-09-202022-09-202015-070929-6646https://scholars.lib.ntu.edu.tw/handle/123456789/621202Brugada syndrome (BrS) is a hereditable sudden cardiac death (SCD). Mutations in the SCN5A gene (the most common BrS-causing gene) are responsible for 20-25% of this disease in Caucasian populations. However, the prevalence of SCN5A mutations in patients with BrS in the Chinese Han population in Taiwan remains unknown. Therefore, in this study, we investigated the prevalence of the SCN5A mutation in the largest BrS cohort in Taiwan.enBrugada syndrome; SCN5A mutations; Taiwan; sodium channel[SDGs]SDG3Unique clinical characteristics and SCN5A mutations in patients with Brugada syndrome in Taiwanjournal article10.1016/j.jfma.2013.02.002261547542-s2.0-84937251722WOS:000359029700009