Cai CHuang J.-JSano KZhu YZhang YWu QZhu BIshida YSHYH-CHYANG LUOLin H.-A.2022-11-162022-11-16202202540584https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125221583&doi=10.1016%2fj.matchemphys.2022.125885&partnerID=40&md5=5014efcb521dbcfa8d0abfdf6c4b24e2https://scholars.lib.ntu.edu.tw/handle/123456789/625226Under light irradiation, corannulene produces toxic reactive oxygen species (ROS), which have potential applications for disease treatment in biological systems. However, no effective functionalization strategy for endowing corannulene with high water solubility and efficient ROS production ability at the same time currently exists. Herein, a new corannulene derivative (EGph-Cora) with five hydrophilic rotating groups, which improve the solubility of the molecule in water and reduce its molecular aggregation, is presented. EGph-Cora exhibits not only high photostability but also high Type I and Type II ROS quantum yields (0.2 and 0.99, respectively). © 2022 Elsevier B.V.Buckybowl; Corannulene; Curved polyaromatic hydrocarbon; Reactive oxygen species; Singlet oxygenOxygen; Buckybowls; Corannulene; Curved polyaromatic hydrocarbon; Disease treatment; Functionalizations; Light irradiations; Polyaromatic hydrocarbons; Reactive oxygen species; Singlet oxygen; Watersoluble; Solubilityjournal article10.1016/j.matchemphys.2022.1258852-s2.0-85125221583