Genetic variants of NTCP gene and hepatitis B vaccine failure in Taiwanese children of hepatitis B e antigen positive mothers

Chen, Ya-HuiYa-HuiChenTsuei, Daw-JenDaw-JenTsueiLai, Ming-WeiMing-WeiLaiWen, Wan-HsinWan-HsinWenChiang, Cheng-LunCheng-LunChiangJIA-FENG WUHUEY-LING CHENHONG-YUAN HSUYEN-HSUAN NIMEI-HWEI CHANG2022-08-222022-08-222022-081936-0533https://scholars.lib.ntu.edu.tw/handle/123456789/617291Hepatitis B virus (HBV) vaccine failure remains a hurdle to the global elimination of HBV infections in the vaccination era. We aimed to elucidate the relationships between HBV entry receptor sodium taurocholate co-transporting polypeptide (NTCP) and vaccine failure in children born to highly infectious mothers.enChronic infection; Genetic variant; HBeAg seroconversion; HBsAg; Hepatitis B virus; IFITM3; NTCP; Type I interferons; Vaccine failure; rs4646287 G > A[SDGs]SDG3Genetic variants of NTCP gene and hepatitis B vaccine failure in Taiwanese children of hepatitis B e antigen positive mothersjournal article10.1007/s12072-022-10350-7356356882-s2.0-85131103025WOS:000802904500001https://scholars.lib.ntu.edu.tw/handle/123456789/612858