Cheng, S.-H.S.-H.ChengLee, C.-H.C.-H.LeeYang, C.-S.C.-S.YangTseng, F.-G.F.-G.TsengCHUNG-YUAN MOULo, L.-W.L.-W.Lo2018-09-102018-09-102009http://www.scopus.com/inward/record.url?eid=2-s2.0-60749090668&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/347735Functionalization of mesoporous silica nanoparticles (MSNs) with Pd-porphyrins for cancer cell photodynamic therapy is reported. The composite platform, MSN-PdTPP, expands the role of Pd-porphyrins from their routine use as phosphorescence probes for oxygen sensing/imaging (diagnostics) to that of novel nano-photosensitizers for cancer cell phototherapy (therapeutics). The utility of MSN-PdTPP in the phototherapeutic treatment of MDA-MB-231 breast cancer cells is also evaluated, suggesting it is a promising cancer theranostic platform. ? 2009 The Royal Society of Chemistry.application/pdf2526987 bytesapplication/pdf[SDGs]SDG3Cells; Nanoparticles; Optical materials; Oxygen; Palladium; Photosensitizers; Plasmons; Porphyrins; Probes; Silica; Breast cancer cells; Cancer cells; Functionalization; Functionalized; Mesoporous silica nanoparticles; Oxygen-sensing; Phototherapy; Theranostics; Photodynamic therapyjournal article10.1039/b816636f2-s2.0-60749090668WOS:000263450300006