Liao, YianYianLiaoYI-KAI CHANGSHUO-MENG WANGHONG-CHIANG CHANG2023-02-092023-02-0920221932-6203https://scholars.lib.ntu.edu.tw/handle/123456789/627805The testosterone to estradiol ratio (T/E2 ratio) reportedly exerts a stronger effect on semen quality and sexual desire than does testosterone alone. Clomiphene citrate is a selective estrogen receptor modulator that has long been used as an empirical treatment option in the management of idiopathic oligozoospermia. Clomiphene may change the hypothalamus-pituitary-gonad axis and result in the alteration of the T/E2 ratio. No reliable data are available regarding the change in the T/E2 ratio after clomiphene use in eugonadism.enSECONDARY HYPOGONADISM; THERAPY[SDGs]SDG3journal article10.1371/journal.pone.0262924351003042-s2.0-85123974753WOS:000801937600026https://api.elsevier.com/content/abstract/scopus_id/85123974753