Implementation of a national bundle care program to reduce central line-associated bloodstream infections in intensive care units in Taiwan

Lai C.-C.Cia C.-T.Chiang H.-T.Kung Y.-C.Shi Z.-Y.Chuang Y.-C.Lee C.-M.Ko W.-C.PO-REN HSUEHfor the Infection Control Society of Taiwan2020-12-182020-12-1820181684-1182https://scholars.lib.ntu.edu.tw/handle/123456789/528204Background/purpose: This study assessed the effect of the central line bundle on the rate of central line-associated bloodstream infections (CLABSI) in intensive care units (ICUs) in Taiwan. Methods: This national study was conducted in 27 ICUs with 404 beds total, including 15 medical ICUs, 11 surgical ICUs, and one mixed ICU. The study period was divided into two phases: a pre-intervention (between June 1, 2011 and October 31, 2011) and intervention phase (between December 1, 2011 and October 31, 2012). Outcome variables, including CLABSI rates (per 1000 catheter-days) and catheter utilization rates, were measured. Results: The overall rate of CLABSI significantly decreased by 12.2% (p < 0.001) from 5.74 per 1000 catheter-days in the pre-intervention phase to 5.04 per 1000 catheter-days in the intervention phase. The catheter utilization rate decreased by 1.1% from 55.3% in the pre-intervention phase to 54.2% in the intervention phase. The decline in CLABSI varied significantly among hospital and ICU levels, except surgical ICUs (p = 0.59). Conclusions: Implementing a multidimensional central-line bundle significantly reduced the rates of CLABSI by 12.2% in nearly all participating ICUs, except surgical ICUs. ? 2017[SDGs]SDG3Article; catheter infection; deterioration; health care utilization; human; intensive care unit; medical intensive care unit; public hospital; surgical intensive care unit; Taiwan; bacteremia; care bundle; catheter; catheter infection; central venous catheterization; classification; clinical trial; comparative study; cross infection; hospital; incidence; infection control; intensive care unit; multicenter study; procedures; protocol compliance; standards; statistics and numerical data; utilization; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Catheters; Cross Infection; Guideline Adherence; Hospitals; Humans; Incidence; Infection Control; Intensive Care Units; Patient Care Bundles; TaiwanImplementation of a national bundle care program to reduce central line-associated bloodstream infections in intensive care units in Taiwanjournal article10.1016/j.jmii.2017.10.001291087832-s2.0-85032882731