Chen K.-T.Chen P.-Y.Tang R.-B.Huang Y.-F.PING-ING LEEYang J.-Y.Chen H.-Y.Bresee J.Hummelman E.Glass R.2021-01-072021-01-0720050022-1899https://www.scopus.com/inward/record.uri?eid=2-s2.0-23944524403&doi=10.1086%2f431495&partnerID=40&md5=f42d6b5eb4b624c81e5d9b12b39ac0b4https://scholars.lib.ntu.edu.tw/handle/123456789/539614We examined the epidemiological profile of rotavirus infection among children hospitalized for diarrhea in Taiwan, to assess the burden of this disease. From 1 April 2001 through 31 March 2003, children <5 years old with gastroenteritis admitted to 4 sentinel hospitals were enrolled in a surveillance study and had stool specimens tested for the presence of rotavirus, enteric adenovirus, and the bacterial pathogens for which routine screening is performed. For 52% of patients, a recognized enteric pathogen was identified, including rotavirus (43% of patients), bacteria (11%), enteric adenovirus (2.5%), and a mixture of pathogens (3.9%). Rotavirus was detected year-round, but great month-to-month variability made it difficult to identify a distinct seasonal pattern. Rotavirus disease was most common among children 7-23 months old, but the rate of rotavirus detection varied little between the youngest and oldest age groups. The novel strain P[8]G9 was detected most commonly (37% of strains), followed by strains P[8]G1 (31%), P[4]G2 (10%), P[8]G3 (9.3%), and P[8]G4 (3.7%). Rotavirus infection is the most important cause of diarrhea among hospitalized children in Taiwan, and a rotavirus vaccination program for young children might significantly reduce this problem. ? 2005 by the Infectious Diseases Society of America. All rights reserved.[SDGs]SDG3Adenovirus; child; conference paper; controlled study; diarrhea; feces analysis; female; gastroenteritis; health survey; human; infant; major clinical study; male; priority journal; Rotavirus; seasonal variation; Taiwan; virus detection; virus infection; virus strain; Diarrhea; Feces; Female; Hospitals; Humans; Infant; Male; Rotavirus; Rotavirus Infections; Sentinel Surveillance; Taiwanconference paper10.1086/431495160888042-s2.0-23944524403