2023-01-012024-05-13https://scholars.lib.ntu.edu.tw/handle/123456789/651058目前在醫療上最前期的診斷指標常為血液生化指標，但生化指標出現時往往受檢個體已經在疾病的模式中，因此許多研究團隊嘗試尋找生物指標 (biomarker)，以期可以在更早期即進行疾病控制，但生物指標的找尋往往需要龐大的經費和時間，且不易以單一指標作為診斷依據。近年來，科學脈診的技術已趨成熟，主要為透過不同經絡的特異性震動頻率作為脈相強弱的判定；目前科學脈診甚至已在部分中醫診所取代傳統脈診。本計畫旨在利用脈診作為早期衰老症診斷的工具，以達可提早干預衰弱症的目的。本計畫目前已收案203人，分別蒐集不同年齡層受試者的脈診以及衰弱指標標，在本計畫第三年將完成500位受試者樣品之收集，分析受試者的衰弱指數與脈診模式之間的關係，並建立具有預測性的脈診圖譜。 Blood biochemistry parameters are now the diagnosis indicator for early detection. However, detecting the blood parameters can only appear in subjects who have been in a disease state. Thus, searching for a better biomarker before diseases have attracted many researchers’ attention. Finding a new biomarker often takes a long time and a big budget, and one biomarker is always insufficient to support the diagnosis. Recently, scientific pulse diagnosis has matured; it displays meridian intensity based on the vibration of every individual meridian. Even some Chinses clinics have replaced traditional pulse diagnosis with scientific pulse diagnosis. This project aims to use scientific diagnosis to detect early frailty to prevent frailty. In the first year, we collected the pulse diagnosis data from 203 subjects with different ages and frailty levels. In this final year, we will analyze the relationship between the results of scientific pulse diagnosis and the level of frailty, followed by establishing a frailty prediction pulse pattern. For this, we can evaluate the efficacy of the platform for frailty improvement and the scientific pulse diagnosis for pre-frailty.衰老症;科學脈診;預測平台;Frailty; scientific pulse diagnosis; prediction platform