口腔生物研究所LEE, BOR-SHIUNNBOR-SHIUNNLEEWANG, CHEN-YINGCHEN-YINGWANGFANG, YEN-YINYEN-YINFANGHSIEH, KUO-HUANGKUO-HUANGHSIEHLIN, CHUN-PINCHUN-PINLIN2012-07-052018-07-092012-07-052018-07-092011http://ntur.lib.ntu.edu.tw//handle/246246/240636INTRODUCTION: We have developed new urethane acrylate-based root canal sealers using polycarbonate (PC) as polyol and 2, 2-azobis(2-methyl) butyronitrile (AMBN) as a thermal initiator. The purpose of this study was to compare the properties among a group of seven sealers: (1) polybutyleneadipate (PBA) with 2,2-azobis-isobutyronitrile ( AIBN), (2) PBA-AMBN, (3) PC-AIBN, (4) PC-AMBN, (5) AH Plus ( Dentsply DeTrey GmbH, Konstanz, Germany), (6) Epiphany ( Pentron Clinical Technologies, Wallingford, CT), and (7) EndoREZ (Ultradent Products, Inc, South Jordan, UT). METHODS : Attenuated total reflectance-Fourier transforming infrared spectroscopy was used to analyze the degree of conversion. Cytotoxicity was evaluated using MTT assay. In addition, push-out bond strength, solubility, and dimensional stability were investigated. RESULTS: Urethane acrylate- based root canal sealers behaved better than Epiphany and EndoREZ for the properties evaluated in this study. The PC- AMBN sealer exhibited the highest degree of conversion even in the apical third, and its cytotoxicity for nonsetting and aged specimens at 24 hours was comparable to AH Plus sealer . In addition, the PC-AMBN sealer with zinc oxide/ thermoplastic polyurethane cones had a significantly higher bond strength than AH Plus with gutta percha. Solubility and dimensional changes of the PC-AMBN sealer conformed to the American National Standards Institute/American Dental Association (ANSI/ADA) standard 57. CONCLUSIONS : The PC-AMBN sealer has great potential for use in endodontic therapy.en-USPropertiesroot canal sealerurethane acrylate