YEN-MING HUANGShiyanbola, Olayinka OOlayinka OShiyanbolaChan, Hsun-YuHsun-YuChan2021-08-042021-08-042018-1107383991https://scholars.lib.ntu.edu.tw/handle/123456789/575965Objective: To investigate whether medication self-efficacy moderates or mediates the relationship between health literacy and medication adherence. To propose a path model that illustrates the interrelated relationship between health literacy, medication self-efficacy, medication adherence, and hemoglobin A1c (HbA1c). Methods: This cross-sectional study was performed via a face-to-face survey. Factors that may influence medication adherence and HbA1c were identified from the literature review. One hundred and seventy-four participants included were ≥20 years old with diagnosed type 2 diabetes, understood English, and were prescribed at least one oral diabetes medicine. During clinic visits, a questionnaire was administered to evaluate health literacy, medication self-efficacy, and medication adherence. HbA1c values were obtained from electronic medical records. Path analyses were conducted for data analysis. Results: Medication self-efficacy mediated but did not moderate the relationship between numeracy and diabetes medication adherence. Participants with higher numeracy skills may develop a greater level of medication self-efficacy, which in turn may result in a higher level of diabetes medication adherence and a lower level of HbA1c. Conclusion: Enhancing patients' medication self-efficacy and numeracy skills may be imperative in intervention programs to improve diabetes medication adherence. Practice implications: An improvement in numeracy skills and medication self-efficacy is recommended to enhance diabetes medication adherence.enDiabetes; Document literacy; Health literacy; Medication adherence; Numeracy; Self-efficacy[SDGs]SDG3journal article10.1016/j.pec.2018.06.010299357392-s2.0-85048784057https://api.elsevier.com/content/abstract/scopus_id/85048784057