Ko, Yu-LinYu-LinKoJIUNN-LEE LINLei, Meng-IiuanMeng-IiuanLeiChen, Jin-JerJin-JerChenTsou, Shi-ShengShi-ShengTsouKuan, PeiliangPeiliangKuanLien, Wen-PinWen-PinLien2023-08-112023-08-1119950008-6312https://www.scopus.com/record/display.uri?eid=2-s2.0-0029085671&doi=10.1159%2f000176917&origin=inward&txGid=5b433fc7c620d85ffbcbc1c3b43962f6https://scholars.lib.ntu.edu.tw/handle/123456789/634519Apical segmental dysfunction is an unusual finding in hypertrophic cardiomyopathy (HCM). It is characterized by a poor clinical course and a high incidence of malignant ventricular tachyarrhythmias. Long-term prognosis of patients with HCM and apical segmental dysfunction is still unclear. We report 2 cases of apical segmental dysfunction in HCM in whom progressive apical dilatation and congestive heart failure developed. Both patients died suddenly, and intractable ventricular tachyarrhythmias were documented in 1 case during resuscitation. This report provides further evidence that apical segmental dysfunction might predict a subgroup of patients with HCM who are likely to develop end-stage heart failure and are at high risk of sudden cardiac death.enApical segmental dysfunction | Endstage heart failure | Hypertrophic cardiomyopathy[SDGs]SDG3journal article10.1159/00017691775857502-s2.0-0029085671https://api.elsevier.com/content/abstract/scopus_id/0029085671