Kao P.-K.Hsu C.-C.2019-05-172019-05-17201416134982https://scholars.lib.ntu.edu.tw/handle/123456789/409101In this work, we demonstrated an all-dry, top-down, and one-step rapid process to fabricate paper-based microfluidic devices using fluorocarbon plasma polymerization. This process is able to create fluorocarbon-coated hydrophobic patterns on filter paper substrates while maintaining the trench and detection regions intact and free of contamination after the fabrication process, as confirmed by attenuated total reflectance-Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. We have shown that the processing time is one critical factor that influences the device performance. For the device fabricated with a sufficiently long processing time (180 s), the sample fluid flow can be well confined in the patterned trenches. By testing the device with an 800 £gm channel width, a sample solution amount as small as 4.5 £gL is sufficient to perform the test. NO2 - assay is also performed and shows that such a device is capable for biochemical analysis. ? 2014 Springer-Verlag Berlin Heidelberg.journal article10.1007/s10404-014-1347-52-s2.0-84899926162https://www.scopus.com/inward/record.uri?eid=2-s2.0-84899926162&doi=10.1007%2fs10404-014-1347-5&partnerID=40&md5=8c92b177d83f1b0512f4105ce5f779f0