Chuang Y.-M.Tseng S.-P.LEE-JENE TENGHo Y.-C.PO-REN HSUEH2020-03-272020-03-2720060163-4453https://scholars.lib.ntu.edu.tw/handle/123456789/480306We present a diabetic patient with necrotizing fasciitis caused by Citrobacter freundii associated with an injury from the fish fin. Two isolates recovered six days after cefotaxime treatment had a cefotaxime minimum inhibitory concentration (MIC) of 0.12 and 256 mg/L, respectively, and a cefepime MIC of 0.03 and 0.25 mg/L, respectively. The two isolates both possessed blaCMY-2 gene. The patient responded unsatisfactorily to cefotaxime and cefepime therapy and surgical debridement but recovered completely after ertapenem treatment for 42 days. ? 2005 The British Infection Society.[SDGs]SDG3amikacin; amoxicillin; amoxicillin plus clavulanic acid; ampicillin; bacterial protein; beta lactamase; cefazolin; cefepime; cefmetazole; cefotaxime; cefuroxime; ciprofloxacin; clavulanic acid; ertapenem; imipenem; minocycline; piperacillin; piperacillin plus tazobactam; tazobactam; adult; antibiotic resistance; antibiotic sensitivity; article; bacterial gene; bacterium isolate; case report; cellulitis; Citrobacter freundii; debridement; diabetes mellitus; drug hypersensitivity; drug response; Enterobacter infection; erythema; female; fever; human; minimum inhibitory concentration; necrotizing fasciitis; osteomyelitis; skin abscess; treatment failure; Anti-Bacterial Agents; beta-Lactams; Cefotaxime; Cephalosporin Resistance; Cephalosporins; Citrobacter freundii; Enterobacteriaceae Infections; Fasciitis, Necrotizing; Female; Humans; Middle Aged; Osteomyelitis; Wounds and InjuriesEmergence of cefotaxime resistance in Citrobacter freundii causing necrotizing fasciitis and osteomyelitisjournal article10.1016/j.jinf.2005.11.002163759732-s2.0-33747174229