Yang, Chang-HaoChang-HaoYang2006-07-262018-07-122006-07-262018-07-122003http://ntur.lib.ntu.edu.tw//handle/246246/26731Retinal angiogenesis occurs in a variety of disease, such as proliferative diabetic retinopathy, retinopathy of prematurity, and uveitis. A αvβ3 integrin dependent vascular endothelial cell migration and proliferation may play an important role in the pathogenesis of new vessel formation. Disintegrin, a group of RGD-containing peptides from viper venom, is a strong antagonist of αvβ3 integrin. In this study, the inhibitory effect of disintegrin on angiogenesis was evaluated in vitro by a bovine retinal capillary endothelial (BRCE) cell culture model.application/pdf2791115 bytesapplication/pdfzh-TW國立臺灣大學醫學院眼科[SDGs]SDG3journal articlehttp://ntur.lib.ntu.edu.tw/bitstream/246246/26731/1/912314B002201.pdf