SUNG-HSIN KUOSHIH-HUNG YANGWei, Ming-FengMing-FengWeiLee, Hsiao-WeiHsiao-WeiLeeYU-WEN TIENANN-LII CHENGKUN-HUEI YEH2021-11-262021-11-262021-08-191475-2867https://scholars.lib.ntu.edu.tw/handle/123456789/587898We previously demonstrated that nuclear BCL10 translocation participates in the instigation of NF-κB in breast cancer and lymphoma cell lines. In this study, we assessed whether nuclear BCL10 translocation is clinically significant in advanced and metastatic pancreatic ductal adenocarcinoma (PDAC).enBCL10; NF-κB; Pancreatic cancer; Prognosis[SDGs]SDG3B cell lymphoma/leukemia 10; B-cell lymphoma 3 protein; cyclin A; cyclin B1; cyclin D1; cyclin dependent kinase 1; cyclin dependent kinase 2; cyclin dependent kinase 4; cyclin E; DNA; gemcitabine; immunoglobulin enhancer binding protein; K ras protein; Myc protein; oxaliplatin; protein p21; protein p27; protein tyrosine phosphatase; short hairpin RNA; adult; advanced cancer; aged; animal experiment; animal model; Article; AsPC-1 cell line; BxPC-3 cell line; cancer prognosis; cancer recurrence; cell cycle; cell cycle progression; cell nucleus; cell viability; controlled study; cytoplasm; DNA binding; down regulation; drug cytotoxicity; drug potentiation; flank; G1 phase cell cycle checkpoint; G2 phase cell cycle checkpoint; gene silencing; genetic transfection; human; human cell; immunohistochemistry; inhibition kinetics; inoculation; M phase cell cycle checkpoint; major clinical study; male; metastasis potential; middle aged; mouse; NF kB signaling; nonhuman; overall survival; PANC-1 cell line; pancreas carcinoma; pancreatectomy; protein expression; protein transport; tumor growth; tumor xenograft; very elderly; wild type; young adultjournal article10.1186/s12935-021-02143-z344126312-s2.0-85113185441https://scholars.lib.ntu.edu.tw/handle/123456789/582732