國立臺灣大學電機工程學系暨研究所鍾孝文2006-07-252018-07-062006-07-252018-07-062004-07-31http://ntur.lib.ntu.edu.tw//handle/246246/7995本研究展示穩定態自由旋進影像中水與 脂肪信號分離之可行性。其中心思想為,在採 用TE = TR/2 之穩定態自由旋進技術中,相位 角相對於射頻脈衝基本上只允許兩種角度的 可能:亦即00 與1800。利用此種特性,吾人得 以利用中心頻率偏移的細部調整,在相同的影 像條件之下達到水與脂肪同相(in-phase)或反 相(out-of-phase)的影像,因此,一般磁振造 影所使用的迪克遜法(Dixon method)便可以 應用於此種技術中,經由複數影像的相加與相 減達成水與脂肪信號的分離。在本計畫中,掃 瞄參數TR 與中心頻率偏移量經由理論計算加 以最佳化,同時並在3.0 Tesla 磁振造影系統上 取得八位志願受試者腹部之二維穩定態自由 旋進影像以驗證理論的推測。實驗結果證實本 方法幾可達成接近完全的脂肪信號抑制,並且 比商業化的技術具有更佳的軟組織對比。The feasibility of fat/water separation using the balanced steady-state free precession (SSFP) technique is demonstrated. The key idea is based on the observation that at the nominal values of TE = TR/2 in SSFP imaging, phase coherence could be achieved at essentially only two orientations, namely 00 and 1800 relative to the RF pulses in the rotating frame, under the assumption of TR << T2 and independent of the steady-state free precession angle. This property allows in-phase and out-of-phase SSFP images to be obtained by proper choices of the center frequency offset, hence permitting the Dixon subtraction method to be utilized for effective fat/water separation. The TR and frequency offset for optimal fat/water separation are derived from theories. Experimental results on healthy subjects using a 3.0 Tesla system show that nearly complete fat suppression can be accomplished.application/pdf88963 bytesapplication/pdfzh-TW國立臺灣大學電機工程學系暨研究所脂肪與水分離迪克遜法同相反相 影像穩定態快速成像Fat-water separationDixon methodin-phase out-of-phase imagessteady-state free precession快速穩定態磁振造影及其臨床應用之研究(2/2)Rapid steady-state MR imaging and its clinical applications (2/2)reporthttp://ntur.lib.ntu.edu.tw/bitstream/246246/7995/1/922218E002017.pdf