Chen C.-L.KEH-CHUNG LINChen C.-H.Chen C.-C.Liu W.-Y.Chung C.-Y.Chen C.-Y.Wu C.-Y.2020-03-262020-03-2620102072-0939https://www.scopus.com/inward/record.uri?eid=2-s2.0-77957361049&partnerID=40&md5=bafc24aef6e7e812d5673fea4f837cc2https://scholars.lib.ntu.edu.tw/handle/123456789/479221Background: Speech production is often impaired in children with cerebral palsy (CP). This study investigated the factors associated with motor speech control in children with spastic cerebral palsy. Methods: Thirty-three children with spastic CP who were able to speak were identified for this study. They were classified into two groups: group A (spastic diplegia or hemiplegia, n = 17) and group B (spastic quadriplegia, n = 16). Each child received various assessments, namely cognition, language, modified Verbal Motor Production Assessment for Children (VMPAC), speech intelligibility, CP subtype, and Gross Motor Function Classification System (GMFCS). Results: Group A showed better cognition and language function, higher modified VMPAC scores and better GMFCS levels than group B (p < 0.05). However, the two groups did not significantly differ in speech intelligibility. Linear regression indicated that all modified VMPAC scores were negatively related to CP subtype (adjusted r2 = 0.51~0.63, p < 0.001). The average modified VMPAC scores had a positive relationship with global language scores (adjusted r2 = 0.63, p < 0.001), and the modified VMPAC scores of the sequence subtests were positively related to the full intelligence quotients (adjusted r2 = 0.55, p < 0.001). Conclusion: The findings of this study suggest that motor impairment severity, cognition and language functions are associated with the motor speech control among children with CP.Cerebral palsy; Motor severity; Motor speech control; Oro-motor control; Speech intelligibility[SDGs]SDG3article; auditory comprehension; cerebral palsy; child; clinical article; cognitive defect; comprehension; disease severity; female; focal oromotor control; global language function; global motor control; Gross Motor Function Classification System; human; intelligence quotient; language ability; language disability; male; modified Verbal Motor Production Assessment for Children; motor control; motor dysfunction; motor performance; motor speech control; patient assessment; rating scale; spastic diplegic cerebral palsy; spastic hemiplegic cerebral palsy; spastic quadriplegic cerebral palsy; speech; speech intelligibility; verbal behavior; Cerebral Palsy; Child; Child, Preschool; Cognition; Female; Humans; Linear Models; Male; Motor Skills; Quadriplegia; Speech Intelligibilityjournal article208046712-s2.0-77957361049