Chung, Chi-TingChi-TingChungTUN JAOJEN-JEN SU2025-12-162025-12-162023https://scholars.lib.ntu.edu.tw/handle/123456789/734668The Heidenhain variant Creutzfeldt-Jakob disease (CJD) is characterized by isolated visual symptoms at disease onset, which may mimic numerous ophthalmological disorders. Anti-recoverin autoantibody can be found in patients with autoimmune-related retinopathies. The presence of this antibody with visual symptoms might be confusing in the early stages of the Heidenhain variant CJD. We describe the first case of an anti-recoverin antibody found in the Heidenhain variant CJD who presented with progressive blurred vision then memory deterioration proceeded later. This presentation reinforces the concept that the presence of the anti-recoverin antibody could not exclude the possibility of the Heidenhain variant of CJD in highly suspicious patients with initial isolated visual disturbance.enAnti-recoverin antibodyCreutzfeldt-Jakob disease (CJD)Heidenhain variant CJDautoimmune-related retinopathiesisolated visual symptoms[SDGs]SDG3journal article10.1080/19336896.2023.222352737337645