KEH-CHUNG LINChang Y.-F.Wu C.-Y.Chen Y.-A.2020-03-262020-03-2620091545-9683https://www.scopus.com/inward/record.uri?eid=2-s2.0-66249139899&doi=10.1177%2f1545968308328719&partnerID=40&md5=deaa267f0695ed8e7b9612e0e1bfe170https://scholars.lib.ntu.edu.tw/handle/123456789/479228Background and Objective. This study investigated the relative effects of distributed constraint-induced therapy (CIT) and bilateral arm training (BAT) on motor performance, daily function, functional use of the affected arm, and quality of life in patients with hemiparetic stroke. Methods. A total of 60 patients were randomized to distributed CIT, BAT, or a control intervention of less specific but active therapy. Each group received intensive training for 2 hours/day, 5 days/week, for 3 weeks. Pretreatment and posttreatment measures included the Fugl?€"Meyer Assessment (FMA), Functional Independence Measure (FIM), Motor Activity Log (MAL), and Stroke Impact Scale (SIS). The proximal and distal scores of FMA were used to examine separate upper limb (UL) elements of movement. Results. The distributed CIT and BAT groups showed better performance in the overall and the distal part score of the FMA than the control group. The BAT group exhibited greater gains in the proximal part score of the FMA than the distributed CIT and control groups. Enhanced performance was found for the distributed CIT group in the MAL, the subtest of locomotion in the FIM, and certain domains of the SIS (eg, ADL/IADL). Conclusion. BAT may uniquely improve proximal UL motor impairment. In contrast, distributed CIT may produce greater functional gains for the affected UL in subjects with mild to moderate chronic hemiparesis.[SDGs]SDG3adult; aged; article; bilateral arm training; constraint induced therapy; controlled study; daily life activity; female; function test; functional assessment; Functional Independence Measure; hemiparesis; human; intermethod comparison; locomotion; major clinical study; male; motor performance; muscle training; quality of life; stroke; Activities of Daily Living; Adult; Aged; Aged, 80 and over; Arm; Disability Evaluation; Exercise Therapy; Female; Functional Laterality; Hand Strength; Humans; Male; Middle Aged; Movement; Muscle Weakness; Outcome Assessment (Health Care); Paresis; Quality of Life; Recovery of Function; Restraint, Physical; Stroke; Young Adultjournal article10.1177/1545968308328719191181302-s2.0-66249139899