Yu, Z.-H.Z.-H.YuWu, C.-M.C.-M.WuLin, Y.-W.Y.-W.LinChuang, M.-L.M.-L.ChuangTsai, J.-C.J.-C.TsaiSun, C.-W.C.-W.SunJUI-CHE TSAI2018-09-102018-09-102008http://www.scopus.com/inward/record.url?eid=2-s2.0-42149114502&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/340821Diffuse optical tomography (DOT) is a technique to assess the spatial variation in absorption and scattering properties of the biological tissues. DOT provides the measurement of changes in concentrations of oxy-hemoglobin and deoxyhemoglobin. The oxygenation images are reconstructed by the measured optical signals with nearest-neighbor pairs of sources and detectors. In our study, a portable DOT system is built with optode design on a flexible print circuit board (FPCB). In experiments, the hemodynamics temporal evolution of exercises and vessel occlusions are observed with in vivo measurements form normal subjects and some patients in intensive care unit.Cardiovascular diseases; Diffuse optical tomography; Vessel occlusion[SDGs]SDG3Absorption; Architectural design; Computer networks; Diagnostic radiography; Hemodynamics; Intensive care units; Light scattering; Measurements; Medical imaging; Optical tomography; Optics; Refraction; Scattering; Sulfur compounds; Thermography (temperature measurement); Tissue; Tomography; Bio-medical applications; Biological tissues; Cardiovascular disease (CVD); deoxy hemoglobin; Diffuse optical tomography (DOT); dot system; In-vivo measurements; Intensive care; Nearest Neighbor (NN); Optical signalling; scattering properties; Spatial variations; temporal evolutions; Imaging techniquesconference paper10.1117/12.764561