Chen, Shin-PinShin-PinChenSu, Jui-HsinJui-HsinSuAhmed, Atallah FouadAtallah FouadAhmedCHANG-FENG DAIWu, Yang-ChangYang-ChangWuSheu, Jyh-HorngJyh-HorngSheu2009-12-172018-06-282009-12-172018-06-282007http://www.scopus.com/inward/record.url?eid=2-s2.0-35648995364&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/330534http://ntur.lib.ntu.edu.tw/bitstream/246246/174453/1/69.pdfNew xeniaphyllane-derived metabolites (1-7) were isolated from the EtOAc extract of the Formosan soft coral Sinularia gibberosa. The structures and relative configurations of these compounds were elucidated on the basis of extensive spectroscopic analysis (including 2D NMR) and by comparison of their spectral data with those of related compounds. In vitro cytotoxic evaluation of the above metabolites towards a limited panel of cancer cell lines is also described. ? 2007 Pharmaceutical Society of Japan.application/pdf124466 bytesapplication/pdfen-USSinularia gibberosa; Soft coral; Xeniaphyllane-derived[SDGs]SDG3gibberosin g; gibberosin h; gibberosin i; gibberosin j; gibberosin k; gibberosin l; gibberosin m; natural product; terpenoid derivative; unclassified drug; xeniaphyllane; antineoplastic activity; article; breast carcinoma; cancer cell culture; cancer research; cell strain HepG2; controlled study; coral; cytotoxicity; cytotoxicity test; drug isolation; human; human cell; in vitro study; liver cell carcinoma; lung carcinoma; nuclear magnetic resonance; Sinularia gibberosa; spectroscopy; Acetates; Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Sesquiterpenes; Terpenesjournal article10.1248/cpb.55.14712-s2.0-35648995364WOS:000250805800010http://ntur.lib.ntu.edu.tw/bitstream/246246/174453/1/69.pdf