Altered glycosylation of Tamm-Horsfall glycoprotein derived from renal allograft recipients leads to changes in its biological function

Wu, Tsai-HungTsai-HungWuSONG-CHOU HSIEHKO-JEN LICHENG-HAN WUCHIA-LI YUYang, An-HangAn-HangYangTsai, Chang-YouhChang-YouhTsai2022-02-102022-02-102008-010966-3274https://scholars.lib.ntu.edu.tw/handle/123456789/594010Human urinary Tamm-Horsfall glycoprotein (THP) is a pleotropic protein that binds different cytokines and stimulates various immunocompetent cells. It is unclear whether these important functions of THP are altered in renal transplant patients.enNF-kappa B p52; proinflammatory cytokine-binding activity; renal allograft transplantation; Tamm-Horsfall glycoprotein (THP); TUMOR NECROSIS FACTOR; POLYMORPHONUCLEAR NEUTROPHILS; TUBULOINTERSTITIAL NEPHRITIS; COMPLEMENT 1Q; PROTEIN BINDS; URINARY-TRACT; UROMODULIN; CELLS; GENE; CARBOHYDRATEAltered glycosylation of Tamm-Horsfall glycoprotein derived from renal allograft recipients leads to changes in its biological functionjournal article10.1016/j.trim.2007.07.001180479312-s2.0-36349015388WOS:000251922400005https://scholars.lib.ntu.edu.tw/handle/123456789/542207