CHEN, S. C.S. C.CHENCHANG, C. F.C. F.CHANGJOU, L. J.L. J.JOUCHUNG-MIN LIAO2010-01-062018-06-292010-01-062018-06-292006http://ntur.lib.ntu.edu.tw//handle/246246/176024Vaccination has proved a powerful defence against measles. We reappraise measles seroepidemiological data in Taiwan from 1974 to 2004 having robust age-stratified serological information on exposure and immunity to quantitatively characterize measles vaccination programmes. We dynamically model measles seroepidemiology to estimate age-dependent intensity of infection associated with the effects of different contact patterns on pre- and post-vaccination. The WAIFM (who acquires infection from whom) contact matrix is employed to describe the transmission between and within each age group. A deterministic SEIR (susceptible-exposed-infected-recovery) model is used to capture subpopulation dynamics. Our study shows that mass regional or nationwide vaccination programmes could greatly reduce the potential for a major measles epidemic and have strong direct effects on the potential impact of childhood vaccination. We parameterize a predictive model that should reduce the socio-economic costs of measles surveillance in Taiwan and thereby encourage its continuance, especially for preschool children ? 2006 Cambridge University Press.application/pdf253208 bytesapplication/pdfen-US[SDGs]SDG3measles vaccine; adolescent; adult; article; child; controlled study; cost control; data analysis; epidemic; epidemiological data; health program; human; infant; infection control; infection risk; mathematical model; measles; Measles virus; outcome assessment; prediction; preventive health service; risk assessment; seroprevalence; socioeconomics; Taiwan; virus transmission; Adolescent; Adult; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Measles; Measles Vaccine; Models, Biological; Taiwan; Vaccinationjournal article10.1017/S09502688060073692-s2.0-34547457206http://ntur.lib.ntu.edu.tw/bitstream/246246/176024/1/73.pdf