Association between short-term exposure to air pollution and sudden infant death syndrome

WU-SHIUN HSIEHPau-Chung CHENChen, Chi-JenChi-JenChenChen, Mei-HueiMei-HueiChenCHIEN-YI CHENPO-NIEN TSAOHUNG-CHIEH CHOUPAU-CHUNG CHEN2021-04-192021-04-192021-0500456535https://scholars.lib.ntu.edu.tw/handle/123456789/556677The association between air pollution and infant mortality has been inconsistently reported. A few studies have estimated short-term effects of air pollution on infants' health. This population-based case-control study aimed to examine the potential effects of air pollution on sudden infant death syndrome (SIDS) in the post-neonatal period in Taiwan during 1997-2002. Each case of infant death was matched with 20 randomly selected sex-matched controls who were born on the same day and were still alive. We obtained 24-h measurements of air pollutants and meteorological factors in each case and control with 1- to 14-day lags from 55 air-quality monitoring stations. After controlling for potential confounders, conditional logistic regression analysis was performed to estimate effects of air pollutants on SIDS (n = 398) and respiratory death (n = 121) among neonates. In single- and multi-pollutant models, we found that 100-ppb increment in carbon monoxide (Odds Ratio = 1.04-1.07) and 10-ppb increment in nitrogen dioxide (Odds Ratio = 1.20-1.35) with 1- to 14-day lags were associated with significant increase in SIDS, although a significant relationship between air pollution and respiratory death was not determined in 1- to 14-day lags. Short-term carbon monoxide and nitrogen dioxide exposure were associated with significant increase in SIDS in the post-neonatal period, with latency estimated within days before death.enAir pollution; Infant mortality; Multi-pollutant model; SIDS[SDGs]SDG3Air quality; Carbon monoxide; Logistic regression; Nitrogen oxides; Quality control; Air quality monitoring stations; Conditional logistic regressions; Meteorological factors; Nitrogen dioxides; Potential effects; Short-term effects; Short-term exposure;Association between short-term exposure to air pollution and sudden infant death syndromejournal article10.1016/j.chemosphere.2020.129515334504222-s2.0-85099185464https://scholars.lib.ntu.edu.tw/handle/123456789/541738https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099185464&doi=10.1016%2fj.chemosphere.2020.129515&partnerID=40&md5=0472ccb2a04c04db66b918497c9ab107