Chuang, Chen HanChen HanChuangWu, Lu WeiLu WeiWuCheng, Zhi HaoZhi HaoChengYA-YU CHIANG2023-09-222023-09-222018-01-019781510897571https://scholars.lib.ntu.edu.tw/handle/123456789/635641In this work, we are the first to generate a novel, energy free liquid delivery method utilizing by osmotic pressure in the microfluidic device. The semi-permeable biomimetic membrane properties, total transferred volume and flow rate were evaluated. A universal osmotic outlet plug is developed as a negative pressure for standard PMMA and PDMS microfluidic devices. The reverse salt flux is investigated to prove the biocompatibility of the osmotic outlet plug. We further demonstrated a precise single macrophages position application using osmotic outlet plug. This osmotic outlet plug provides similar functionality to traditional syringe pump but opens a great potential to make the portable device miniaturization to be true.Energy free liquid delivery method | Osmosis | Passive | Pumplessconference paper2-s2.0-85079824301https://api.elsevier.com/content/abstract/scopus_id/85079824301