Peng Y.-S.JENQ-WEN HUANGKUAN-YU HUNGLin B.-S.Lin C.-Y.Yang C.-S.Chen T.-W.Hsia C.-C.Chen D.-L.Hsu W.-D.Chang C.-F.KWAN-DUN WULin R.-P.TUN-JUN TSAIChen W.-Y.2020-12-242020-12-2420131121-8428https://www.scopus.com/inward/record.uri?eid=2-s2.0-84877314261&doi=10.5301%2fjn.5000153&partnerID=40&md5=d86e3f7e21de6ed0d87300986a4b6c71https://scholars.lib.ntu.edu.tw/handle/123456789/531801Hemodialysis patients suffer from poor quality of life and survival. A retrospective cohort study was performed to examine the sex differences in selfreported quality of life and mortality in a Taiwanese hemodialysis cohort. Methods: A total of 816 stable hemodialysis patients were included. Patients completed two questionnaires: the 36-item Short Form Health Survey Questionnaire (SF-36, Taiwan Standard Version 1.0) to assess health-related quality of life (HRQoL) and the Beck Depression Inventory (BDI, Chinese Version) to assess depressive mood. Mortality outcomes were recorded for a seven-year follow-up period. Results: After adjustment for confounding factors, women had significantly higher BDI scores (P=.003), lower physical functioning (P<.001), bodily pain (P<.001), mental health (P=0007), and physical component scale (PCS) scores (P<.001). There were 284 deaths recorded. In the Cox-proportional hazard model, women had significantly lower mortality than men (P<.001). Conclusions: Women on hemodialysis had more depression-related symptoms and poor self-reported HRQoL, but better survival than men. The sex difference in psychological and HRQoL issues deserves greater concern because this relates to clinical care and further study. ? 2012 Societ? Italiana di Nefrologia.[SDGs]SDG3albumin; creatinine; adult; albumin blood level; article; Beck Depression Inventory; clinical assessment; cohort analysis; creatinine blood level; depression; diabetes mellitus; female; follow up; functional status; hemodialysis; hemodialysis patient; human; major clinical study; male; mental component scale; mental health; mortality; pain; physical capacity; physical component scale; quality of life; rating scale; retrospective study; self report; sex difference; Short Form 36; social interaction; survival rate; Taiwan; Adult; Aged; Depression; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Odds Ratio; Proportional Hazards Models; Quality of Life; Renal Dialysis; Retrospective Studies; Risk Factors; Self Report; Severity of Illness Index; Survival Rate; Taiwan; Time Factors; Treatment Outcomejournal article10.5301/jn.5000153226415792-s2.0-84877314261