2014-01-012024-05-13https://scholars.lib.ntu.edu.tw/handle/123456789/643453摘要：酵母菌是一種重要且最早被科學家們所建立的模式生物系統，其歷史已超過七十年。許多突破性的科學發展均利用酵母菌為模式生物系統，包括 2013 年諾貝爾獎得主Randy Schekman 在囊泡傳遞的調控機制偉大研究發現。在臺灣，有超過四十個實驗室以酵母菌為主要研究工具來探討重要之生物現象。目前台灣酵母菌生物資源中心負責統籌國內酵母菌之資料及生醫研究的菌種收集、交換、交流和提供實驗方法等作業。酵母菌研討會對於交流研究發現、資訊、菌種資源及研究構想是非常重要的。因此，於西元 2000 年在沒有任何經費補助的情況下舉辦國內第一次酵母菌研討會。至今，每年舉行的酵母菌研討會約有超過 200 位學生及科學家共襄盛舉。在臺灣，我們擁有實力堅強的酵母菌研究團隊，且能夠發表研究論文於 Cell、Science 、Genes and Development 及 PNAS 等國際知名期刊。為了整合國內所有酵母菌研究資源，國科會已在 2011 年補助成立台灣酵母菌生物資源中心。本中心以獲得絕大多數台灣酵母菌研究學者的支持，應永續經營以作為研究資源交流之平臺，將可加速臺灣利用酵母菌模式生物研究領域之發展，並能達到世界一流的研究水準。<br> Abstract: Yeast S. cerevisiae has been introduced as an experimental model system for more than seventy years. Dr. Randy Schekman used a brilliantly conceived yeast genetic screen to isolated sec mutants that accumulate secretory pathway intermediates. He cloned the corresponding genes and established biochemical reactions that faithfully reproduced specific secretory pathway events. Dr. Randy Schekman was awarded the Nobel Prize for Physiology or Medicine in 2013. In Taiwan, there are more than forty laboratories use yeast as a research model to investigate the important biological questions and human diseases. Currently Taiwan yeast bio-resources center serves the yeast scientific community for collecting and distributing experimental yeast strains. The center also provides the exchanging experimental materials and methods for yeast research. Without the financial support from government, the yeast research community has been holding a meeting annually since 2000. Up to now, there are more than 200 scientists and students attend the meeting annually. We have a very strong yeast research community in Taiwan and several laboratories has been published many outstanding papers in international prestigious journal such as; Cell, Science, and Genes and Development, PNAS et. al.. To integrate the resources of all yeast research laboratories in Taiwan, NSC began to support the Yeast Bio-resources Center in 2011. All the members of yeast research community expressed their appreciation for support from NSC and hope the center can be a platform for exchanging all the research materials and methods, including yeast stains, gene construction tools and vectors, antibodies, genetic manipulation and cell biology techniques. We anticipate that the Yeast Bio-resources Center can promote the establishment of world class of research findings and reports from Taiwan yeast research community.