Chau-Chin W.Wu-Shiung H.Yasuo T.JUI-CHANG TSAIChee-Yin C.2020-02-272020-02-2719930168-583Xhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-43949169712&doi=10.1016%2f0168-583X%2893%2995642-I&partnerID=40&md5=97d8b7aa8e8bb1c4c799c95828522f1bhttps://scholars.lib.ntu.edu.tw/handle/123456789/465298We have synthesized a rare earth metal with porphyrin to obtain a lanthanoid porphynato for biomedical applications. Some of the lanthanoid porphynatos are potentially the versatile cancer probes. We report gadolinium hematoporphyrin derivative synthesis and show that PIXE can be used to assess how good the synthesis is and how good the gadolinium hematoporphyrin derivative system can be used as a tumor localizer to probe a malignant neoplasia from its benigh periphery. We show the PIXE spectra of a nude mouse experiment to explain our works. Theoretically the present approach can allow us to investigate carcinogenesis at the cell level. ? 1993.[SDGs]SDG3journal article10.1016/0168-583X(93)95642-I2-s2.0-43949169712