Jack Tan W.C.Inoue K.AbdelWareth L.Giannitsis E.Kasim S.Shiozaki M.Aw T.C.Cheng F.Dung H.T.Li Y.-H.Lim S.H.Lukito A.A.Than M.Chu F.-Y.Devasia T.CHIEN-CHANG LEEPhrommintikul A.Youn J.-C.Chew D.P.2020-03-242020-03-2420201346-9843https://scholars.lib.ntu.edu.tw/handle/123456789/478194The Asia-Pacific Society of Cardiology (APSC) high-sensitivity troponin T (hs-TnT) consensus recommendations and rapid algorithm were developed to provide guidance for healthcare professionals in the Asia-Pacific region on assessing patients with suspected acute coronary syndrome (ACS) using a hs-TnT assay. Experts from Asia-Pacific convened in 2 meetings to develop evidence-based consensus recommendations and an algorithm for appropriate use of the hs-TnT assay. The Expert Committee defined a cardiac troponin assay as a high-sensitivity assay if the total imprecision is ?10% at the 99th percentile of the upper reference limit and measurable concentrations below the 99th percentile are attainable with an assay at a concentration value above the assay’s limit of detection for at least 50% of healthy individuals. Recommendations for single-measurement rule-out/rule-in cutoff values, as well as for serial measurements, were also developed. The Expert Committee also adopted similar hs-TnT cutoff values for men and women, recommended serial hs-TnT measurements for special populations, and provided guidance on the use of point-of-care troponin T devices in individuals suspected of ACS. These recommendations should be used in conjunction with all available clinical evidence when making the diagnosis of ACS. ? 2020 Japanese Circulation Society. All rights reserved.[SDGs]SDG3troponin T; biological marker; troponin T; acute coronary syndrome; advisory committee; algorithm; Asia Pacific Society of Cardiology; clinical assessment; computed tomographic angiography; consensus; coronary angiography; diagnostic accuracy; disease assessment; electrocardiogram; emergency ward; enzyme assay; enzyme blood level; health care personnel; heart infarction; heart muscle injury; heart muscle ischemia; high sensitivity troponin t assay; hospital mortality; human; limit of detection; medical society; mortality; non ST segment elevation myocardial infarction; percutaneous coronary intervention; point of care testing; predictive value; Review; risk assessment; sensitivity analysis; sensitivity and specificity; ST segment elevation myocardial infarction; acute coronary syndrome; blood; cardiology; cardiology service; cardiovascular system examination; decision support system; decision tree; hospital emergency service; practice guideline; prognosis; reproducibility; upregulation; Acute Coronary Syndrome; Algorithms; Biomarkers; Cardiology; Cardiology Service, Hospital; Consensus; Decision Support Techniques; Decision Trees; Diagnostic Techniques, Cardiovascular; Emergency Service, Hospital; Humans; Predictive Value of Tests; Prognosis; Reproducibility of Results; Societies, Medical; Troponin T; Up-RegulationReview10.1253/circj.CJ-19-0874318528632-s2.0-85079527388