2009-03-302024-05-13https://scholars.lib.ntu.edu.tw/handle/123456789/652403摘要:台灣本土樹種相思樹(Acacia confusa Merr.)廣泛分布於山地及丘陵,為台灣傳統用藥。由本研究室先前的研究結果顯示相思樹抽出物具有良好之抗氧化與抗發炎活性,至於相思樹抽出物及其成分抑制黃嘌呤氧化酶活性,則尚無相關的研究報告,因此,本計畫擬評估相思樹乙醇抽出物及其成分抑制黃嘌呤氧化酶活性。而本計畫如能順利完成,將可了解相思樹乙醇抽出物及其成分抑制黃嘌呤氧化酶活性,並使具有抑制黃嘌呤氧化酶活性之成分應用於痛風用藥之開發。<br> Abstract: Acacia confusa Merr. (Leguminosae), a native species in Taiwan, is widely distributed on the hills and lowlands of Taiwan, and has been traditionally used as a medicine. Results from our previous studies demonstrated that crude extracts from A. confusa had excellent antioxidant and anti-inflammatory activities. However, to the best of our knowledge there are no prior studies on XOD-inhibitory activity of crude extracts and their constituents from A. confusa. Therefore, the objective of this project is to evaluate XOD-inhibitory activity of ethanolic extracts and their constituents from A. confusa. Through this study, it is expected that XOD-inhibitory constituents from A. confusa ethanolic extracts have great potential as a source for gout drugs.相思樹抽出物黃嘌呤氧化酶痛風用藥植化物Acacia confusaExtractsXanthine oxidasegout drugsphytochemical相思樹抽出物及其成分作為痛風用藥之開發