2001-08-012024-05-18https://scholars.lib.ntu.edu.tw/handle/123456789/704210摘要：臺灣得天獨厚的地理環境，蘊育了許多深受世界各國研究人員注目之珍貴數種。事實上，木材性質與木材抽出成分有著密不可分之關係，且獨特的樹種中往往具有一些特殊成分。因此，若能自本土樹木中尋求具生物活性之成分，鑑定其結構並釐清其作用之機制，將可賦予森林利用新的價值與潛能。本計畫擬選擇臺灣特產並具研究潛力之針葉樹種，如:臺灣杉…等樹種，分別萃取木材、樹皮及葉的抽出成分，進行包括抗真菌、抗細菌、抗白蟻、抗和抗腫瘤等生物活性之篩選。即利用管柱層析、氣相層析及高效能液相層析等技術，分離、純化並收集具生物活性之成分。之後，續運用質譜分析，紅外光光譜分析，碳譜與氫譜核磁共振光譜分析…等光譜分析，鑑定具生物活性成分之確切結構。本計畫如能順利完成，則可確定對不同生物或腫瘤細胞具有抑制作用之成分，甚或了解其作用機制，如此將有助於擴展本土樹種加工利用之潛能與應用領域。<br> Abstract: Being richly endowed by nature, there are many precious tree species grown in Taiwan. It is the fact that there is an intimate relationship between wood properties and its extractives. Different wood species and even various parts of the same tree, such as stem, leaves, and bark, vary distinguishably with respect to both amount and chemical compositions of extractives. Therefore, to identify the bioactive components from the diversified wood extractives and to clarify the mechanisms of their bioactive functions could provide an opportunity to expand the potential utilization of tree. In this study, the bioactive compounds that isolated from the extractives of wood, bark, and leaves of the endemic trees in Taiwan, such as Taiwania cryptomerioides, and so on, will be examined. The bioactivities investigated include antifungal, antimite, antibacterial, antitermite, and antitumours. Repeatedly through the chromatography separation, spectral analysis, and bioactive assay, the bioactive compounds of conifers indigenous to Taiwan will be confirmed.針葉樹臺灣杉生物活性抽出成分ConiferTaiwania cryptomerioidesBioactivityExtractives