Vo, Tuan N.A.Tuan N.A.VoChen, Pin ChuanPin ChuanChenPAI-SHAN CHENJair, Y. C.Y. C.JairWu, Y. H.Y. H.WuTran, Trung NghiaTrung NghiaTran2024-03-272024-03-272024-01-01979835035792910846999https://scholars.lib.ntu.edu.tw/handle/123456789/641448There is a need for scalable, automated lab-on-chip systems for blood plasma separation that can be applied for diagnostics. Here, we developed a vacuum-actuated peristaltic micropump (VPM) integrating inertial microfluidic technique to separate and collect blood plasma from diluted blood. The device performs blood plasma separation with high efficiency (98.5%), quickly (<1 min), automatically, and with minimal whole blood usage (5 μL). Significantly, very little hemolysis (less than 2%) could be achieved using an inclined wall obstruction design in the vacuum actuator.enBlood Plasma Separation | Hemolysis | Inertial Microfluidics | Micropump[SDGs]SDG3[SDGs]SDG7conference paper10.1109/MEMS58180.2024.104394752-s2.0-85186695454https://api.elsevier.com/content/abstract/scopus_id/85186695454