J. ChenM. O’DellW. HeL.J. DuP.-C. LiJ. GaoPAI-CHI LI李百祺2019-10-242019-10-2420178997071https://scholars.lib.ntu.edu.tw/handle/123456789/427910Objective To assess differences in biceps brachii muscle (BBM) stiffness as evaluated by ultrasound shear wave elastography (SWE). Methods The passive stiffness of the BBM was quantified with shear wave velocity (SWV) measurements obtained from 10 healthy volunteers (5 men and 5 women, mean age 50?years, age range 42–63 years) with the elbow at full extension and 30° flexion in this IRB-approved study. Potential differences between two depths within the muscle, two elbow positions, the two arms, and sexes were assessed by using two-tailed t-test. The reproducibility of SWV measurements was tested by using intraclass correlation coefficient (ICC). Results Significantly higher passive BBM stiffness was found at full elbow extension compared to 30° of flexion (p???0.00006 for both arms). Significantly higher passive stiffness in women was seen for the right arm (p?=?0.04 for both elbow positions). Good correlation of shear wave velocity measured at the different depths. The ICC for interobserver and intraobserver variation was high. Conclusions SWE is a reliable quantitative tool for assessing BBM stiffness, with differences in stiffness based on elbow position demonstrated and based on sex suggested. ? 2017 Elsevier Inc.Acoustic radiation force impulse; Biceps brachii muscle; Reproducibility; Shear wave elastography[SDGs]SDG3Acoustic wave velocity; Acoustics; Medical imaging; Muscle; Shear waves; Stiffness; Ultrasonics; Wave propagation; Acoustic radiation Force Impulse; Biceps brachii muscle; Intraclass correlation coefficients; Intraobserver variations; Potential difference; Reproducibilities; Shear wave elastography; Shear wave velocity; Shear flow; adult; Article; biceps brachii muscle; body position; controlled study; correlation coefficient; elastograph; elbow position; extension reflex; female; flexor reflex; human; human tissue; interobserver variation; intraobserver variation; male; middle aged; muscle rigidity; priority journal; reflex; reproducibility; sex difference; shear wave elastography; shear wave velocity; two tailed test; diagnostic imaging; echography; elastography; elbow; joint characteristics and functions; observer variation; pathology; procedures; sex factor; skeletal muscle; standards; validation study; Adult; Elasticity Imaging Techniques; Elbow; Elbow Joint; Female; Humans; Male; Middle Aged; Muscle, Skeletal; Observer Variation; Range of Motion, Articular; Reproducibility of Results; Sex Factors; Ultrasonographyjournal article10.1016/j.clinimag.2017.05.0172-s2.0-85020034194