CHIH-TING LINKao, Ming-TseMing-TseKaoKurabayashi, KatsuoKatsuoKurabayashiMeyhofer, EdgarEdgarMeyhofer2018-09-102018-09-102008http://www.scopus.com/inward/record.url?eid=2-s2.0-44449115225&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/340650We developed a molecular sorter that operates without external power or control by integrating the microtubule-based, biological motor klnesin into a microfluidic channel network to sort, transport, and concentrate molecules. In our devices, functlonalized microtubules that capture analyte molecules are steered along kinesin-coated microchannel tracks toward a collector structure, concentrated, and trapped. Using fluorescent analyte molecules and nanoliter sample volumes, we demonstrated 14 fM sensitivity, even In the presence of high concentrations of other proteins.journal article10.1021/nl072742x2-s2.0-44449115225