Lin C.-S.Chang C.-C.Lee Y.-W.Liu C.-C.Yeh C.-C.YI-CHENG CHANGChuang M.-T.Chang T.-H.Chen T.-L.Liao C.-C.2022-03-102022-03-1020192077-0383https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063076705&doi=10.3390%2fjcm8010100&partnerID=40&md5=843f9cae1274dd71a23d7631aa838853https://scholars.lib.ntu.edu.tw/handle/123456789/596988The impact of diabetes on perioperative outcomes remains incompletely understood. Our purpose is to evaluate post-operative complications and mortality in patients with diabetes. Using the institutional and clinical databases of three university hospitals from 2009–2015, we conducted a matched study of 16,539 diabetes patients, aged >20 years, who underwent major surgery. Using a propensity score matching procedure, 16,539 surgical patients without diabetes who underwent surgery were also selected. Logistic regressions were used to calculate the odds ratios (ORs) with 95% confidence intervals (CIs) for post-operative complications and in-hospital mortality associated with diabetes. Patients with diabetes had a higher risk of postoperative septicemia (OR 1.33, 95% CI 1.01–1.74), necrotizing fasciitis (OR 3.98, 95% CI 1.12–14.2), cellulitis (OR 2.10, 95% CI 1.46–3.03), acute pyelonephritis (OR 1.86, 95% CI 1.01–3.41), infectious arthritis (OR 3.89, 95% CI 1.19–12.7), and in-hospital mortality (OR 1.51, 95% CI 1.07–2.13) compared to people without diabetes. Previous admission for diabetes (OR 2.33, 95% CI 1.85–2.93), HbA1c >8% (OR 1.96, 95% CI 1.64–2.33) and fasting glucose >180 mg/dL (OR 1.90, 95% CI 1.68–2.16) were predictors for post-operative adverse events. Diabetes patients who underwent surgery had higher risks of infectious complications and in-hospital mortality compared with patients without diabetes who underwent similar major surgeries. ? 2019 by the authors. Licensee MDPI, Basel, Switzerland.Adverse outcomes; Diabetes; Fasting glucose; Surgeries[SDGs]SDG3hemoglobin A1c; acute heart infarction; acute kidney failure; acute pyelonephritis; adult; adverse outcome; aged; Article; case control study; cellulitis; cerebrovascular accident; chronic obstructive lung disease; comparative study; controlled study; deep vein thrombosis; diabetes mellitus; female; glucose blood level; hospital admission; hospital mortality; human; infection; infectious arthritis; insulin dependent diabetes mellitus; lung embolism; major clinical study; major surgery; male; middle aged; multicenter study; mycosis; necrotizing fasciitis; operation duration; osteomyelitis; pneumonia; postoperative complication; postoperative hemorrhage; propensity score; septicemia; surgical infection; urinary tract infectionjournal article10.3390/jcm80101002-s2.0-85063076705