Lai C.-C.UN-IN WUJANN-TAY WANGSHAN-CHWEN CHANG2020-12-242020-12-2420130929-6646https://www.scopus.com/inward/record.uri?eid=2-s2.0-84883559678&doi=10.1016%2fj.jfma.2012.09.021&partnerID=40&md5=f4f616b37674a44e704864f9504d0850https://scholars.lib.ntu.edu.tw/handle/123456789/532747Among 15 174 non-duplicated Enterobacteriaceae isolates, the prevalence of carbapenem-nonsusceptible Enterobacteriaceae (CNSE) was about 2.5% at a teaching hospital in Taiwan during 2010. Among 117 available isolates of CNSE, 8.6% carried genes encoding carbapenemases. Tigecycline and colistin were the most active agents against carbapenemase-producing and non-producing isolates. Patients infected with CNSE had an all-cause in-hospital mortality of 37.3%, and mortality was similar for infections from carbapenemase producers and non-producers (14-day mortality rates: 22.2% and 21.5%; 30-day mortality rates: 22.2% and 32.3%, respectively). Continuous surveillance of CNSE is recommended in Taiwan. ? 2012.[SDGs]SDG3amikacin; carbapenem; carbapenemase; cefepime; cefotaxime; cephalosporin; colistin; flomoxef; imipenem; meropenem; moxifloxacin; quinoline derived antiinfective agent; tigecycline; abdominal infection; adult; aged; antibiotic sensitivity; article; bacteremia; bacterium isolate; controlled study; Enterobacteriaceae; Enterobacteriaceae infection; female; human; lower respiratory tract infection; major clinical study; male; minimum inhibitory concentration; mortality; nonhuman; prevalence; skin infection; soft tissue infection; Taiwan; teaching hospital; treatment outcome; urinary tract infection; carbapenemase; ertapenem-nonsusceptible Enterobacteriaceae; minimal inhibitory concentration; treatment outcomes; Aged; Aged, 80 and over; Bacterial Proteins; beta-Lactamases; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Hospitals, Teaching; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Taiwan; Treatment Outcomejournal article10.1016/j.jfma.2012.09.021240166142-s2.0-84883559678