Adzrago, DavidDavidAdzragoSU-WEI WONGWilkerson, Johnny MichaelJohnny MichaelWilkerson2023-07-212023-07-212022-01-0115571874https://scholars.lib.ntu.edu.tw/handle/123456789/633997The association between symptoms of a major depressive episode (MDE) and binge drinking has mixed results. This study examined the association between binge drinking and symptoms of an MDE and other substance use such as illicit drug use and marijuana use. Data were extracted from the 2019 National Survey on Drug Use and Health. A weighted multivariable logistic regression analysis was used to determine the association between binge drinking and MDE symptoms. Weighted moderation analyses were performed to determine whether the effects of MDE symptoms on binge drinking varied by needing treatment for substance use disorders, other substances use, and sociodemographic factors. People who engaged in binge drinking were within ages 18–25 or 26–34, males, non-Hispanic Whites, had some college credit but no degree, and had a total family income of $75,000 or more. People who had MDE symptoms had lower odds of binge drinking, but people who needed treatment for illicit drug or alcohol use, used marijuana, and used illicit drug other than marijuana had higher odds of binge drinking. Race/ethnicity and illicit drug use other than marijuana moderated the association between MDE symptoms and binge drinking, respectively. The hypothesis that binge drinking and symptoms of an MDE and other substance use could be associated was partially supported by our findings. Future longitudinal studies could be useful to further assess whether changes in symptoms of an MDE and other substances use will lead to increases in binge drinking behavior.enAlcohol use | Illicit drug use | Marijuana use | Mental health disorder symptoms[SDGs]SDG3journal article10.1007/s11469-022-00770-92-s2.0-85124726911https://api.elsevier.com/content/abstract/scopus_id/85124726911