Hung M.-N.SHEY-YING CHENWang J.-L.SHAN-CHWEN CHANGPO-REN HSUEHLiao C.-H.YEE-CHUN CHEN2021-12-012021-12-0120051684-1182https://www.scopus.com/inward/record.uri?eid=2-s2.0-33644538934&partnerID=40&md5=3756e28e045094993524a55533dde76bhttps://scholars.lib.ntu.edu.tw/handle/123456789/589296A prospective observational study was conducted to evaluate the clinical characteristics and outcome of community-acquired anaerobic bacteremia. From June 1 2001 through May 31 2002, 52 patients with community-acquired anaerobic bacteremia were enrolled at the emergency department in a teaching hospital. There were 19 patients (34%) with polymicrobial bacteremia and Escherichia coli was the most common copathogen (n = 6). Of 62 anaerobic isolates, species of the Bacteroides fragilis group were the most common isolates (n = 28, 45%), followed by Clostridium spp. (n = 11, 18%). Among the 52 patients enrolled, up to 27% had underlying malignancy and the gastrointestinal tract accounted for 48% of the sources of infection. Clinical manifestations suggesting anaerobic infections were common and three-quarters (n = 39) of 52 patients received adequate empirical antimicrobial treatment. Documentation of anaerobic bacteremia seldom influenced antimicrobial treatment. The 30-day mortality was 25%. Although univariate analysis revealed that underlying malignancy (p=0.003), leukopenia (p=0.044) and absence of fever (p=0.047) were associated with mortality, only malignancy (p=0.007) was an independent risk factor in the multivariate analysis.[SDGs]SDG3antibiotic agent; adolescent; adult; agar gel diffusion; aged; anaerobic infection; antimicrobial therapy; article; bacteremia; Bacteroides fragilis; clinical feature; Clostridium; controlled study; emergency ward; Escherichia coli; female; gastrointestinal infection; human; major clinical study; male; prospective study; teaching hospital; Academic Medical Centers; Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Bacteria, Anaerobic; Bacteroides fragilis; Clostridium; Community-Acquired Infections; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Taiwanjournal article163413452-s2.0-33644538934