國立臺灣大學應用力學研究所本研究完成非侵入式動脈血管阻抗量 測技術。由於血管阻抗描述血壓與血流 脈波頻譜的動態比值關係，代表該位置下 游血管負載。我們利用臨床超音波系統都 卜勒血流頻譜，結合觸診壓力計，取得阻 抗特性，可以協助血管相關疾病診斷。由 於胸腹腔大動脈血管近乎彈性，血壓難以 在體外量測，我們可由血管管壁之脈動近 似估算血壓脈波。週邊血管血壓因受到 黏彈特性的影響，無法以管壁之脈動代 替。本系統經過假體及動物實驗的校正， 效果良好。並以腹腔動脈、頸動脈及週 邊血管阻抗為例，結果顯示單側阻塞性腦 中風病人正常邊阻抗變化不大，阻塞邊之 阻抗明顯增加。而單側出血性之中風病人 兩邊低頻阻抗皆比正常人高。高血壓病患 之動脈阻抗，在靠近心臟之大血管與周邊 血管都比一般人高，其趨勢也一致。邵耀華2006-08-232018-06-292006-08-232018-06-291999-07-31http://ntur.lib.ntu.edu.tw//handle/246246/29686application/pdf925149 bytesapplication/pdfzh-TW國立臺灣大學應用力學研究所非侵入式超音波動脈阻抗In this studya non-invasive arterial impedance measurement technique is developed. Since the vascular impedance describes the spectral relationship of blood pressure and flowit is an important index for vascular load downstream. By combining the ultrasound Doppler and tonometry pressure transducerthe vascular impedance can be calculated. Since the central artery is nearly elasticthe blood pressure is directly related to the change of diameter. For the peripheral arteriesthe palpating pressure is recorded to account for the vascular visco-elasticity. Vascular impedance was demonstrated at the abdominal aortacommon carotid artery and peripheries. We found the abnormal side of stroke patients with one-side occlusion had a higher mean resistance than the normal side. In patients with one-side hemorrhagic infarctionboth of their CCA impedance increased due to higher afterload. The hypertensive patients showed consistent higher arterial impedance than normal from the central to peripheries.Non-invasiveUltrasoundVascular impedancereporthttp://ntur.lib.ntu.edu.tw/bitstream/246246/29686/1/882314B002200M08.pdf